Mitral regurgitation primarily results in which of the following?

Mitral regurgitation primarily results in increased preload. This condition occurs when the mitral valve does not close properly during ventricular contraction, allowing blood to flow back from the left ventricle into the left atrium instead of being ejected into the aorta. As a result, there is an increase in the volume of blood that remains in the left atrium. Consequently, this backflow of blood leads to an elevated volume of blood returning to the left ventricle during diastole, effectively increasing the preload.

Preload refers to the volume of blood in the ventricles at the end of diastole, prior to contraction. The consequence of this increased preload can often lead to volume overload of the heart, which may cause the left ventricle to dilate and possibly lead to heart failure if the condition is chronic. Understanding preload dynamics is essential in assessing hemodynamics and the implications of mitral regurgitation on cardiac function.